The Arrival of DNA Testing

Prior to the development of RFLP (Restriction Fragment Length Polymorphism) in the 1980s, no single procedure seemed to dominate the field of DNA paternity testing. Its high power of discrimination (paternity probabilities exceeding 99.999%) lent it credibility, and RFLP dominated the industry for several years.

Although the paternity tests was quite powerful, and extremely accurate, RFLP was an expensive procedure that relied heavily upon high-quality DNA and a tedious investment of time and labor. DNA research soon sought a testing method that would permit more and faster testing, at lower cost, and with similar levels of reliability. A decade later, a procedure called PCR (Polymerase Chain Reaction) would revolutionize the DNA testing industry, earning its inventor, Kary B. Mullis, the 1993 Nobel Prize in chemistry.

PCR is an inexpensive, automatable procedure, which can be used to analyze poor quality DNA samples, such as those found at crime scenes. The procedure works extremely well with minuscule amounts of DNA, and can achieve the same power of exclusion as RFLP. Without the invention of PCR, the DNA testing, life science and genetics industries could not have seen its rapid growth of the past decade.

The DNA paternity test of the future will offer significantly more information than whether two individuals are related by blood. Imminent (and some current) developments will focus more acutely upon genetic health applications, from inherited health conditions and nutritional deficiencies to early condition diagnoses and prevention of adverse drug reactions. DNA Worldwide’s active involvement in genuine scientific advancement takes specific aim at helming technological breakthroughs in the field of genetics; as the DNA research community continues to develop in size and scope, and genetics databases grow in breadth and complexity, advances in ancestral genetics will naturally follow suit.

With existing technologies capable of accurately measuring connections as diverse as cousinship and avuncular (aunts/uncles) relatedness - and beyond, the future of DNA relationship testing is certain to extend well past merely a few degrees of biological separation. Additionally, DNA Worldwide is committed to developing technologies and processes that will streamline the entire genetics testing operation, optimizing data collection to improve accuracy and speed, and reduce costs.

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